Tag: PEEP
Balancing the Breath: Navigating the Brain-Lung Connection in Acute Brain Injury
This study explores the delicate tug-of-war between mechanical ventilation (MV) and outcomes for patients with Acute Brain Injury (ABI). The researchers highlight that the way we breathe for a patient can significantly influence... read more
Lost in Translation: Unmasking the Silent Struggle of Ineffective Ventilator Efforts
While identifying the subtle timing mismatches between a patient and a ventilator often requires specialized internal monitoring, clinicians can still spot major "asynchronies" by closely watching the flow and pressure curves... read more
Refining Neuromuscular Blockade Use in ARDS
Acute Respiratory Distress Syndrome (ARDS) remains a critical challenge in medicine, persistently linked to mortality rates exceeding 30% despite extensive research over the years. The lack of effective drug treatments means... read more
Beyond the Basics: New Respiratory Markers Predict Extubation Failure
A multicenter study focused on high-risk patients who successfully passed a conventional 30-minute Spontaneous Breathing Trial (SBT) found that standard measures alone are insufficient to predict extubation failure. Extubation... read more
Lung Protection Saves Brains: Low Tidal Volume Tied to Lower Mortality
This international cohort study involving 1,510 patients with Acute Brain Injury (ABI) across 73 ICUs investigated the impact of Low-Tidal-Volume Ventilation (LTVV) on outcomes. In this group, where the most common etiology... read more
PEEP’s Hidden Impact: The Rise in Mechanical Power
This study investigated how a stepwise increase in Positive End-Expiratory Pressure (PEEP) affects respiratory mechanics and mechanical power in mechanically ventilated adults. Using an incremental titration strategy,... read more
Mastering Non-Invasive Respiratory Support: A Guide to Success
This clinical guide provides an overview of non-invasive respiratory support (NIRS) techniques—including High-Flow Nasal Therapy (HFNT), Continuous Positive Airway Pressure (CPAP), and Bilevel Positive Airway Pressure (BiPAP)-for... read more
The Crystal Ball of the ICU: Machine Learning Predicts Who’s Staying and Who’s Not
The PREMIER Study dove into the data of 996 patients experiencing Acute Hypoxemic Respiratory Failure (AHRF) who had been on mechanical ventilation (MV) for at least two days, aiming to develop a reliable way to predict their... read more
Voice Breakthrough: Bringing Speech Back to Ventilator Patients
This retrospective cohort study investigated the safety and success of placing a speaking valve in-line with the mechanical ventilator circuit for critically ill, tracheostomized patients who struggled to wean from the ventilator. Study... read more
Individualizing PEEP in Acute Brain Injury
The consensus is that Positive End-Expiratory Pressure (PEEP) can be safely used in most patients with Acute Brain Injury (ABI), provided its effects on the brain are closely monitored. PEEP Safety and ICP: While PEEP... read more
Endotracheal Intubation Preoxygenation in Resource-limited Settings
Optimal preoxygenation strategies for endotracheal intubation (ETI) in LRS require both protocol adaptation and clinical resourcefulness. An individualized approach using the most feasible combination of techniques should... read more
Electrical Impedance Tomography for PEEP Titration in ARDS Patients
ARDS patients may benefit from electrical impedance tomography (EIT)-guided positive end-expiratory pressure (PEEP) titration. The real-time bedside assessment of regional ventilation provided by EIT may result in improved... read more
Machine Learning to Predict Extubation Success Using the SBT
Among the predictive models that used MOT, VCD, and the spontaneous breathing trial (SBT) as input variables through five machine learning techniques, decision trees and artificial neural networks demonstrated the best diagnostic... read more
Mortality Predictor with sPAP in Elderly Critically Ill with Severe COVID-19 Pneumonia
Mortality in general ARDS patients remains high, with many experiencing long-lasting sequelae. Numerous studies have been conducted to identify predictors of mortality in COVID-19 patients, particularly regarding right ventricular... read more
APRV vs. BIPAP Ventilation in COVID-19 Associated ARDS
Despite of higher mean tidal volumes and higher mean airway pressures in airway pressure release ventilation (APRV) vs. biphasic positive airway pressure (BIPAP), both modes did not present an increased risk of volu- or barotrauma... read more
The Advanced Ventilator Book
The Advanced Ventilator Book is a companion to the best-selling The Ventilator Book and is written for clinicians who already have a solid foundation in the basics of mechanical ventilation. It goes beyond the ventilator... read more
Successful Treatment of Unilateral Pulmonary Edema as Minimally Invasive Mitral Valve Surgery Complication
We successfully treated this patient using ECMO and independent lung ventilation. Several cases have been described in the literature, but the pathogenesis and risk factors of UPE remain unclear. Management depends on... read more
Pitfalls in the Management of Mechanical Ventilation: ARDS and Hypermetabolic States
Mechanical ventilation (MV) is a lifesaving intervention for patients with respiratory failure due to acute respiratory distress syndrome (ARDS) and septic shock. ARDS was first recognized in the late 1960s, approximately... read more
Impacts of Initial ICU Driving Pressure on Outcomes in Acute Hypoxemic Respiratory Failure
Driving pressure (DP) is a marker of severity of lung injury in patients with acute respiratory distress syndrome (ARDS) and has a strong association with outcome. However, it is uncertain whether limiting DP can reduce... read more
Spontaneous Breathing Trials Should Be Adapted for Each Patient According To The Critical Illness
Unassisted SBTs, namely PSV0PEEP0 and T-piece trial, are the most appropriate to replicate the postextubation effort to breathe. In this multicentre randomized cross-over study, adult intensive care unit patients under... read more
Pulmonary Barotrauma in COVID-19 Patients: Experience From a Tertiary University Hospital
Mechanical ventilation (MV) in COVID-19 patients is often complicated with pulmonary barotrauma. The aim of this study was to determine the incidence and risk factors associated with the development of pulmonary barotrauma... read more
Respiratory Effort in Mechanical Ventilation Weaning Prediction
This study demonstrates that PMI and ΔPocc are effective in predicting weaning outcomes in patients with DT≥2mm. The effectiveness of P0.1 in assessing weaning is also significantly higher in this subgroup. These findings... read more
