A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

Several studies were published to validate quick-SOFA (qSOFA), namely in comparison with Systemic Inflammatory Response Syndrome (SIRS) criteria. We performed a systematic review and a meta-analysis with the aim of comparing... read more

New Sepsis Definition (Sepsis-3) and Community-acquired Pneumonia Mortality

New Sepsis Definition (Sepsis-3) and Community-acquired Pneumonia Mortality

qSOFA and CRB outperformed SIRS and presented better clinical usefulness as prompt tools for patients with community-acquired pneumonia in the emergency department. Among the tools for a comprehensive patient assessment,... read more

Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department

Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department

In this multicenter prospective cohort study involving 879 patients with suspected infection treated at the emergency department, the qSOFA was better at predicting in-hospital mortality with an area under the receiver operating... read more

Bad news for sepsis-3.0: qSOFA fails validation

Bad news for sepsis-3.0: qSOFA fails validation

Sepsis 3.0 replaced the SIRS criteria with a new risk-stratification tool, qSOFA. qSOFA was initially developed within the Sepsis-3 publication itself. Until now, qSOFA has never been validated. The value of qSOFA vs. SIRS... read more