Tag: research
Lab-grown ‘Mini Brains’ Produce Electrical Patterns That Resemble Those of Premature Babies
'Mini brains' grown in a dish have spontaneously produced human-like brain waves for the first time — and the electrical patterns look similar to those seen in premature babies. The advancement could help scientists to... read more
Effect of Bag-Mask Ventilation vs Endotracheal Intubation During CPR on Neurological Outcome After OHCA
Among patients with out-of-hospital cardiorespiratory arrest (OHCA), the use of BMV compared with ETI failed to demonstrate noninferiority or inferiority for survival with favorable 28-day neurological function, an inconclusive... read more
Exploring the Potential Effectiveness of Combining Optimal Nutrition With Electrical Stimulation to Maintain Muscle Health in Critical Illness
This article explores the potential role of nutrition and EMS in maintaining muscle health in critical illness. Within this article, we will evaluate fundamental concepts of muscle wasting and evaluate the effects of EMS,... read more
Erasing Death: The Science That Is Rewriting the Boundaries Between Life and Death
Dr. Sam Parnia, Director of the AWARE Study (AWAreness during REsuscitation) and one of the world's leading experts on the scientific study of death and near-death experiences (NDE), presents cutting-edge research from the... read more
Nurse intuition may play a role in critical-care outcomes
Nurse intuition doesn't sound scientific, but it could play a key role in critical-care outcomes, according to a small study published in DovePress. The researchers conducted a descriptive phenomenological study, interviewing... read more
Never Underestimate the Simple Things We Do To Our Patients
In this compelling episode, Professor Paul Wischmeyer, shares some of his experiences as a patient in the ICU. Since he was 15 he has endured multiple hospitalizations and ICU stays for his inflammatory bowel disease. This... read more
Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated AKI
In this randomized, double-blind, placebo-controlled, dose-finding adaptive phase 2a/2b trial enrolling 301 adults, the optimal therapeutic dose of recombinant alkaline phosphatase was 1.6 mg/kg. Treatment with this dose... read more
Ron Daniels Responds to Study on Sepsis Mortality Rates
New research presented at this year’s ESICM LIVES conference (the annual meeting of the European Society of Intensive Care Medicine) shows that in rich countries overall, mortality from sepsis has fallen by around a quarter... read more
Artificial intelligence system could improve survival for sepsis patients
Researchers supported by the NIHR have created an artificial intelligence system that could help identify the best way to treat patients with sepsis. The system 'learnt' the best treatment strategy for a patient by analysing... read more
Conflicts of interest disclosure forms and management in critical care clinical practice guidelines
The current conflicts of interest (COIs) disclosure forms of selected professional societies provide more attention to financial disclosures and COIs and less attention to detecting and managing intellectual COIs, while rarely... read more
An Incurable Disease Is On The Rise In California, And Scientists Say Climate Change Could Cause It To Spread To Much Of The Western US
A fungus that thrives in dry soil and warm weather has caused a record number of infections in California. Experts fear climate change will cause it to spread across the western US. Valley fever, a fungal disease that infects... read more
Mentorship Malpractice
The word mentorship evokes strong emotional and intellectual chords. In formal parlance, mentorship has been defined as "a dynamic, reciprocal relationship in a work environment between an advanced-career incumbent (mentor)... read more
Clinical Trial Testing Vitamin and Steroid Combination in Sepsis Patients Underway at Emory
A new clinical trial at Emory University and 45 other sites around the U.S. will test a combination of vitamins and steroids in patients diagnosed with sepsis. Sepsis is caused by the body's overwhelming and life-threatening... read more
For Doctors, Delving Deeper as a Way to Avoid Burnout
The consequences of burning out — a phenomenon that rises linearly as a doctor matures, until it finally dies down at about 60 — can be hard to measure. Some solutions to fixing burnout are therefore pragmatic. They involve... read more
The Gender Gap in Critical Care Medicine: How Are We Doing Globally?
Female enrollment into medical schools is increasing worldwide, but gender disparities persist in certain specialties, especially in critical care medicine. Published data on the scale of this issue is scarce and a recent... read more
CT-based Measurements Beat Framingham Risk Score in Predicting Future CVD Events
Assessment of abdominal aortic calcification using computed tomography (CT) is a highly effective predictor of future heart attack and CVD risk, according to research published in Radiology Oct. 2—more effective even than... read more
Stopping ICU delirium by getting patients moving
Doctor says the treatment plan makes a 'massive difference' to those in critical care. Any hospital stay can be traumatic. But 30 percent of patients in intensive care units experience ICU delirium. The rate for... read more
Sepsis: Learn the Signs and Document
Writing in the MJA, researchers have reported the findings of a prospective cohort study comparing estimates of the incidence and mortality of sepsis using clinical diagnosis or the Australian and New Zealand Intensive Care... read more
Physician Well-Being: The Reciprocity of Efficiency, Resilience, Wellness Culture
The quality and safety of patient care, and indeed the very vitality of our health care systems, depend heavily on high-functioning physicians. Yet recent data have revealed an extraordinarily high - and increasing - prevalence... read more
Do Nurse Staffing Ratios Work? New Research Says No
Advocates of mandated staffing ratios say they improve patient outcomes. A recent study finds otherwise. Nurse-to-patient ratios are a hot button issue. Look no further than Massachusetts for an example. After a battle that... read more
New York State Sepsis Reporting Mandate Appears to Improve Care and Reduce Deaths
A New York State requirement that all hospitals report compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality from one of the most common causes of death in those who... read more
Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality
Margaret Parker, MD, MCCM, speaks with Stefanie G. Ames, MD, about the article "Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality," published in the May 2018 issue of Pediatric Critical Care Medicine. Dr. Ames... read more
