Tag: sepsis
A Better Way to Detect Sepsis in Kids in the ED
We have been interested in this question for a long time here at CHOP and have done several interventions over the past several years to try to improve our ability to recognize children with septic shock. When we started... read more
Hospital admissions for sepsis jump 89% in Pennsylvania
The number of Lehigh Valley hospital admissions for sepsis, an increasingly prevalent life-threatening complication from infections, increased by 69 percent over eight years, according to a state report released Wednesday.... read more
Cellular Immunotherapy for Septic Shock
The infusion of freshly cultured allogenic bone marrow derived MSCs into participants with septic shock up to a dose of 3 million cells per kg (250 million cells) appears safe. Ages of participants in the interventional versus... read more
Clinical Review: Paracetamol in fever in critically ill patients
Paracetamol is a synthetic, nonopioid, centrally acting analgesic and antipyretic drug. Its antipyretic effect occurres because it inhibits cyclooxygenase-3 and the prostaglandin synthesis.... read more
Sepsis – Explained in 3 Minutes
Sepsis is an emergency, striking about 30 million people every year, killing 6 to 9 million of them. Learn what sepsis is, and how to identify and treat it in this 3-min video. Please share with your loved ones - it could... read more
Sepsis National Hospital Inpatient Quality Measure
The Center for Medicare and Medicaid Services adopted the Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) performance measure to the Hospital Inpatient Quality Reporting Program in July 2015 to help address the... read more
Raising Sepsis Awareness
Most recent parody created by ILAS (Brazil) aimed at health professionals with English subtitles. Share this video with your multidisciplinary teams because together we can overcome sepsis.... read more
Sepsis Awareness Month
September is Sepsis Awareness month. To mark the occasion we invited Marijke Vroomen Durning, Director of Content at Sepsis Alliance, to tell us more about Sepsis, the organization’s work, and the importance of raising... read more
CDC Urges Early Recognition, Prompt Treatment of Sepsis
The Centers for Disease Control and Prevention today launched Get Ahead of Sepsis, an educational initiative to protect Americans from the devastating effects of sepsis. This initiative emphasizes the importance of early... read more
Septic shock with no diagnosis at 24 hours: a pragmatic multicenter prospective cohort study
The lack of a patent source of infection after 24 hours of management of shock considered septic is a common and disturbing scenario. A multicenter observational cohort study in ten intensive care units (ICU) in France.... read more
Restricting volumes of resuscitation fluid in adults with septic shock after initial management
A protocol restricting resuscitation fluid successfully reduced volumes of resuscitation fluid compared with a standard care protocol in adult ICU patients with septic shock.... read more
Don’t Just Do Something, Stand There!
An excellent analogy on how doing nothing can be the best option. Penalty kicks in soccer can make fans crumple with anguish or weep with elation. The kicker sends the ball rocketing toward the goal and goalkeepers lunge... read more
Quality Improvement Initiatives in Sepsis in an Emerging Country
This quality improvement initiative in sepsis in an emerging country was associated with a reduction in mortality and with improved compliance with quality indicators. However, this reduction was sustained only in private... read more
Noninvasive Ventilation in Patients With Hematologic Malignancy
Two-thirds of patients with Hematologic Malignancy and respiratory failure failed Noninvasive Ventilation (NIV) and required endotracheal intubation, and had high subsequent mortality. Patients who failed NIV had higher Paco2,... read more
Selepressin – An Effective Substitute for Norepinephrine
Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients. Vasopressin is widely used for vasopressor... read more
Incidence, Prevalence, and Management of MRSA Bacteremia Across Patient Populations
Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of morbidity and mortality and can cause metastatic or... read more
Delays in Antibiotic Administration for Sepsis
Todd Fraser, MD, speaks with Christopher W. Seymour, MD, MSc, about the article, "Delays From First Medical Contact to Antibiotic Administration for Sepsis," published in Critical Care Medicine. Dr. Seymour's article contends... read more
Potentially modifiable factors contributing to sepsis-associated encephalopathy
Acute renal failure and common metabolic disturbances represent potentially modifiable factors contributing to sepsis-associated encephalopathy. However, a true causal relationship has yet to be demonstrated. Our study confirms... read more
Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis
Secondary retrospective analysis of a single-center sepsis registry. Vasoactive-Inotropic Score in pediatric sepsis patients is independently associated with important clinically relevant outcomes including ICU length of... read more
SOFA Effective Pediatric Version
An age-adjusted version of the Sequential Organ Failure Assessment score for sepsis has been found to be at least as good, if not better than, other pediatric organ dysfunction scores at predicting in-hospital mortality.... read more
Can Electronic Alerts Help Identify Sepsis in Sick Children?
A two-step electronic alert system successfully reduced missed sepsis diagnoses in children by 76 percent. The new pediatric protocol, which incorporates the use of vital signs, risk factors, and a clinician's judgment,... read more
A Brief Review of Troponin Testing for Clinicians
Current American College of Cardiology and American Heart Association guidelines state that troponin is the preferred biomarker for diagnosing acute myocardial infarction (MI). Troponin T (TnT) and I molecules have amino... read more
