Defining Sepsis on the Wards: Comparing Two Sepsis Definitions

Defining Sepsis on the Wards: Comparing Two Sepsis Definitions

Sepsis is defined as a dysregulated host response to infection, resulting in acute organ dysfunction. Although the condition has been thoroughly studied in the intensive care unit (ICU), accurate data collection outside of... read more

A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

Several studies were published to validate quick-SOFA (qSOFA), namely in comparison with Systemic Inflammatory Response Syndrome (SIRS) criteria. We performed a systematic review and a meta-analysis with the aim of comparing... read more

Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department

Evaluating the Validity of Sepsis-3 Criteria in the Emergency Department

In this multicenter prospective cohort study involving 879 patients with suspected infection treated at the emergency department, the qSOFA was better at predicting in-hospital mortality with an area under the receiver operating... read more

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

Sepsis-3 definitions predict ICU mortality in a low-middle-income country

The medical records of 957 patients were retrieved from a prospectively collected database. Serum lactate improved accuracy for values higher than 4 mmol/L in the no-dysfunction and septic shock groups.... read more

Belgian scientists discover missing link in septic shock

Belgian scientists discover missing link in septic shock

Researchers at VIB and Ghent University have discovered an important mechanism of sepsis, an overreaction of the body’s immune system to an infection.... read more

Is SIRS dead? The new definition of sepsis.

Is SIRS dead? The new definition of sepsis.

To mark Sepsis Awareness Month in September, Prof Gando, Editor-in-Chief of Journal of Intensive Care, tells us more about the recent sepsis definitions, published earlier this year.... read more