Number Needed to Treat

Effectively communicating clinical trial results to patients and clinicians is a requirement for appropriate application in clinical practice. In a recent issue of JAMA, Zhao et al1 reported the results from a randomized... read more

UV Light Reduces Hospital-acquired Infections

A new study published in the American Journal of Infection Control (AJIC) shows that ultraviolet (UV) disinfection technology, called PurpleSun, eliminates up to 97.7 percent of pathogens in the operating room (OR). Using... read more

Prehospital Intravenous Fentanyl Administered by Ambulance Personnel

Prehospital acute pain is a frequent symptom that is often inadequately managed. The concerns of opioid induced side effects are well-founded. To ensure patient safety, ambulance personnel are therefore provided with treatment... read more

Catheter-Directed Therapy for PE Built on Fallacy

Tissue plasminogen activator has a notoriously checkered past within emergency medicine, and its controversial use continues with the advent of targeted therapy for pulmonary embolism. Catheter-directed administration of... read more

Study Shows How Bacteria Spread from Sink Drainpipes to Patients

Many recent reports have found multidrug resistant bacteria living in hospital sink drainpipes, putting them in close proximity to vulnerable patients. But how the bacteria find their way out of the drains, and into patients... read more

ICU May Be Overused for Some COPD, Acute MI, HF Patients

For patients with COPD, heart failure and myocardial infarction, who are not critically ill, a stay in the ICU may be no more beneficial than staying on a ward, according to an analysis just published in the Annals of the... read more

The effects of performance status one week before hospital admission on the outcomes of critically ill patients

PS impairment was associated with worse outcomes independently of other markers of chronic health status, particularly for patients in the medium range of severity of illness. PS impairment was moderate in 17.3 % and severe... read more

Ultrasound-guided Pleural Effusion Drainage With a Small Catheter Using the Single-step Trocar or Modified Seldinger Technique

Ultrasound-guided pleural effusion drainage by catheter insertion is a safe and effective procedure. The success rate is low when the effusion is loculated and septated. Both the trocar and the modified Seldinger techniques... read more

One of the Deadliest Hospital-Acquired Infections Is Preventable

Johns Hopkins Study Shows One of the Deadliest Hospital-Acquired Infections Is Preventable. For some hospital patients, going on a ventilator is often the difference between life and death. About 800,000 hospital patients... read more

Hemodynamic Support after Cardiac Surgery

Low cardiac output syndrome is a common complication of cardiac surgery and is associated with increased mortality. Levosimendan has been shown in small studies to be an effective therapy.... read more

Antifungal Treatment in the ICU

Invasive fungal infections (IFIs) are a major cause of morbidity and mortality in critically ill patients. Almost 80% of IFIs are due to Candida spp., which are the third most common isolated microorganisms in the intensive... read more

Electrophysiological Investigations of Peripheral Nerves and Muscles

Resting trans-membrane potential difference (Em) of skeletal muscle is correlated to the energy status of the organism: the more severe the illness, the lower the Em. In 1971, Cunningham demonstrated this association with... read more

Hoopla Aside, hs-cTnI is Not Catching Missed Mis

We have been searching for a tool to identify myocardial infarction patients who are truly safe for discharge ever since Pope, et al., found that we were discharging two percent of patients with MIs from the emergency department.... read more

Aid Tool Does Not Help Care Decisions in Prolonged Mechanical Ventilation

Treatment decisions commonly have to be made in intensive care units (ICUs). These decisions are difficult for surrogate decision makers and often lead to decisional conflict, psychological distress, and treatments misaligned... read more

Medical Dispatchers’ Perception of Visual Information in Real Out-of-hospital Cardiac Arrest

Providing medical dispatchers with visual information from the location of OHCA might improve their understanding of the OHCA-scenario, which might enhance communication, their ability to guide more bystanders and improve... read more

Widespread use of Chlorhexidine Doesn’t Promote Resistance in S. Aureus

Investigators from the University of Nebraska Medical Center (UNMC) Division of Infectious Diseases recently published reassuring data indicating that use of chlorhexidine (CHG) to bathe hospitalized patients does not lead... read more

The Effect of Defining COPD by the Lower Limit of Normal of FEV1/FVC Ratio in TIOSPIR Participants

Using the lower limit of normal to define airflow obstruction would have excluded patients in TIOtropium Safety and Performance In Respimat study with a higher risk of nonfatal major adverse cardiovascular events and a lower... read more

When is Patient Feedback Valid? Supporting Patient Feedback as a Catalyst for Change

As part of the revalidation process, doctors must collect patient feedback at least once every five years. While it is encouraging to see patient feedback included in this process, questions must be asked about what message,... read more

Recommendations on the Use of Ultrasound Guidance for Adult Thoracentesis

The use of ultrasound guidance for thoracentesis has been associated with increased success rates and decreased complication rates. Ultrasound can be used to estimate the pleural fluid volume, characterize the effusion as... read more

Optimizing Patient and Family Education Resources for the ICU

Offering stronger patient and family education tools in the ICU will ease patient and caregiver fears and make them more comfortable with the care setting. An integrated, centralized, and digital platform is best suited for... read more

The Psychological Impact of Intensive Care

A period in intensive care is known to negatively affect patients' long term physical, cognitive and psychiatric health, in what's known as post-intensive care syndrome (PICS). Researchers from the University of Oxford sought... read more

50 States Ranked by Amount of Active Nurses

California contains the most professionally active registered nurses in the U.S. with 337,738 RNs, according to a ranking from the Kaiser Family Foundation. The ranking is based on October 2018 data compiled by Redi-Data... read more