Tag: study
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
Effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock. Despite a progressive increase in mortality... read more
Delirium, Frailty, and Mortality: Interactions in a Prospective Study of Hospitalized Older People
Although delirium and frailty contribute to mortality, the overall impact of delirium on admission appears to be greater at lower levels of frailty. In contrast to the hypothesis that there is a bimodal distribution for mortality,... read more
Association of Inferior Vena Cava Filter Placement for Venous Thromboembolic Disease and a Contraindication to Anticoagulation With 30-Day Mortality
After adjustment for immortal time bias, Inferior Vena Cava (IVC) filter placement was associated with increased 30-day mortality in patients with venous thromboembolic disease (VTE) and a contraindication to anticoagulation.... read more
Timing of Infectious Disease Clinical Rotation Is Associated With Infectious Disease Fellowship Application
During a 7-year period, those interns randomly assigned to rotate on ID in the first 6 months of their intern year were more likely to become future ID applicants. This supports prior self-reported survey data that early... read more
Out-of-hours Discharge from ICU, In-hospital Mortality and ICU Readmission Rates
Out-of-hours discharge from an ICU is strongly associated with both in-hospital death and ICU readmission. These effects persisted across all definitions of “out of hours” and across healthcare systems in different geographical... read more
Ultrasound Non-invasive Measurement of Intracranial Pressure in Neurointensive Care
Of the studied ultrasound nICP methods, ONSD is the best estimator of Intracranial Pressure (ICP). The novel combination of ONSD ultrasonography and vTCD of the straight sinus is a promising and easily available technique... read more
Intravenous Fish Oil (Omegaven) Approved by FDA
Intravenous Fish Oil (Omegaven) approved by FDA for use in total parenteral nutrition (TPN) in pediatric patients in the United States. Omegaven 10% Emulsion is a fish oil emulsion administered intravenously in patients who... read more
The Effect of Alcohol Consumption on the Risk of ARDS
Chronic high alcohol consumption significantly increases the risk of ARDS. This finding suggests that patients admitted to hospital should be screened for chronic alcohol use. Seventeen observational studies (177,674 people)... read more
Effect of In-Bed Leg Cycling and Electrical Stimulation of the Quadriceps on Global Muscle Strength in Critically Ill Adults
In this single-center randomized clinical trial involving patients admitted to the ICU, adding early in-bed leg cycling exercises and electrical stimulation of the quadriceps muscles to a standardized early rehabilitation... read more
How You Can Protect Your Parent From Delirium
Unlike dementia, which is constant and gets progressively worse, delirium tends to come and go, fluctuating even in the course of a day. The symptoms are transitory, yet for people who develop delirium, it can be the start... read more
Low-dose vs. High-dose Magnesium in Rapid Afib
Magnesium sulfate has been used as an adjunct medication for the treatment of atrial fibrillation (AF) due to its ability to lessen sinus node depolarization via calcium antagonism. Prior studies investigating magnesium in... read more
Difficult-to-Treat Resistance in Gram-negative Bacteremia at 173 US Hospitals: Retrospective Cohort Analysis of Prevalence, Predictors, and Outcome of Resistance to All First-line Agents
Nonsusceptibility to first-line antibiotics is associated with decreased survival in GNBSIs. DTR is a simple bedside prognostic measure of treatment-limiting coresistance. The Premier Database was analyzed for inpatients... read more
Controversial US Ketamine Trial Sparks Ethics Complaint
Advocacy group alleges that emergency medical workers in Minnesota gave patients ketamine injections without consent, despite known risks. A consumer-advocacy group is filing a complaint with the US government about two clinical... read more
Variability in Antibiotic Use Across PICUs
Margaret Parker, MD, MCCM, speaks with Thomas V. Brogan, MD, about the article "Variability in Antibiotic Use Across PICUs," published in the June 2018 issue of Pediatric Critical Care Medicine. Dr. Brogan discusses study... read more
Quality and Quantity of Sleep and Factors Associated With Sleep Disturbance in Hospitalized Patients
This study demonstrated that the duration and quality of sleep in hospitalized patients were significantly affected and revealed many potentially modifiable hospital-related factors negatively associated with sleep. Raising... read more
Effect of Decompressive Laparotomy on Organ Function in Patients with Abdominal Compartment Syndrome
Decompressive laparotomy has been advised as potential treatment for abdominal compartment syndrome (ACS) when medical management fails; yet, the effect on parameters of organ function differs markedly in the published literature.... read more
Pediatric Sepsis Care Within an Hour Decreases Chance of Death
More than one in 10 children hospitalized with sepsis die, but when a series of clinical treatments and tests is completed within an hour of its detection, the chances of survival increase considerably, according to a new... read more
Providing Psychological Support to People in Intensive Care
The Provision Of Psychological support to People in Intensive Care (POPPI) psychological intervention to reduce acute patient stress in critical care and prevent future psychological morbidity was feasible and acceptable.... read more
AKI and Electrolyte Disorders in the Critically Ill Patient with Cancer
This review outlines key knowledge areas for critical care physicians and nephrologists caring for patients with cancer and associated kidney issues such as acute kidney injury (AKI) and electrolyte disorders. Specifically,... read more
Operator performs robot-assisted PCI from 100 miles away
Tele-stenting appears more possible now than ever, as Vascular Robotics announced an interventional cardiologist used its CorPath GRX System to perform a remote percutaneous coronary intervention (PCI) in a pig 100 miles... read more
Skeletal Muscle Dysfunction in COPD. What We Know and Can Do for Our Patients
Skeletal muscle dysfunction occurs in patients with chronic obstructive pulmonary disease (COPD) and affects both ventilatory and nonventilatory muscle groups. It represents a very important comorbidity that is associated... read more
Doctors Rely on More than Just Data for Medical Decision Making
Many technology companies are working on artificial intelligence systems that can analyze medical data to help diagnose or treat health problems. Such systems raise the question of whether this kind of technology can perform... read more
