Effect of Decompressive Laparotomy on Organ Function in Patients with Abdominal Compartment Syndrome

Decompressive laparotomy has been advised as potential treatment for abdominal compartment syndrome (ACS) when medical management fails; yet, the effect on parameters of organ function differs markedly in the published literature.... read more

Effect of Decompressive Laparotomy on Organ Function in Patients with Abdominal Compartment Syndrome

Pediatric Sepsis Care Within an Hour Decreases Chance of Death

More than one in 10 children hospitalized with sepsis die, but when a series of clinical treatments and tests is completed within an hour of its detection, the chances of survival increase considerably, according to a new... read more

Pediatric Sepsis Care Within an Hour Decreases Chance of Death

Providing Psychological Support to People in Intensive Care

The Provision Of Psychological support to People in Intensive Care (POPPI) psychological intervention to reduce acute patient stress in critical care and prevent future psychological morbidity was feasible and acceptable.... read more

Providing Psychological Support to People in Intensive Care

AKI and Electrolyte Disorders in the Critically Ill Patient with Cancer

This review outlines key knowledge areas for critical care physicians and nephrologists caring for patients with cancer and associated kidney issues such as acute kidney injury (AKI) and electrolyte disorders. Specifically,... read more

AKI and Electrolyte Disorders in the Critically Ill Patient with Cancer

Operator performs robot-assisted PCI from 100 miles away

Tele-stenting appears more possible now than ever, as Vascular Robotics announced an interventional cardiologist used its CorPath GRX System to perform a remote percutaneous coronary intervention (PCI) in a pig 100 miles... read more

Operator performs robot-assisted PCI from 100 miles away

Skeletal Muscle Dysfunction in COPD. What We Know and Can Do for Our Patients

Skeletal muscle dysfunction occurs in patients with chronic obstructive pulmonary disease (COPD) and affects both ventilatory and nonventilatory muscle groups. It represents a very important comorbidity that is associated... read more

Skeletal Muscle Dysfunction in COPD. What We Know and Can Do for Our Patients

Doctors Rely on More than Just Data for Medical Decision Making

Many technology companies are working on artificial intelligence systems that can analyze medical data to help diagnose or treat health problems. Such systems raise the question of whether this kind of technology can perform... read more

Doctors Rely on More than Just Data for Medical Decision Making

Chest Compression Rates and Pediatric In-hospital Cardiac Arrest Survival Outcomes

Non-compliance with compression rate Guidelines was common in this multicenter cohort. Among ICU patients, slightly lower rates were associated with improved outcomes compared to Guidelines.Prospective observational study... read more

Chest Compression Rates and Pediatric In-hospital Cardiac Arrest Survival Outcomes

Auditory Icon Alarms Are More Accurately and Quickly Identified than Current Standard Melodic Alarms in a Simulated Clinical Setting

Under our simulated conditions, anesthesia providers more correctly and quickly identified icon alarms than standard alarms. Subjects were more likely to perceive higher fatigue and task load when using current standard alarms... read more

Auditory Icon Alarms Are More Accurately and Quickly Identified than Current Standard Melodic Alarms in a Simulated Clinical Setting

Vascular Effects of Adrenomedullin and the Anti-Adrenomedullin Antibody Adrecizumab in Sepsis

Sepsis remains a major scientific and medical challenge, for which, apart from significant refinements in supportive therapy, treatment has barely changed over the last few decades. During sepsis, both vascular tone and vascular... read more

Vascular Effects of Adrenomedullin and the Anti-Adrenomedullin Antibody Adrecizumab in Sepsis

Hemophagocytic Lymphohistiocytosis: Potentially Underdiagnosed in ICUs

Overall, 7 out of 9 patients (77.8%) suffering from aHLH remained undiagnosed. Awareness of this life-threatening syndrome, especially in ICUs, should be raised. The inclusion of ferritin into the admission lab panel for... read more

Hemophagocytic Lymphohistiocytosis: Potentially Underdiagnosed in ICUs

Barriers to implementing expert safety recommendations for early mobilization in ICU during mechanical ventilation

Early mobilization in the intensive care unit (ICU) has been consistently reported as feasible and safe with minimal adverse events; however, invasive mechanical ventilation patients are rarely actively mobilized. An expert... read more

Barriers to implementing expert safety recommendations for early mobilization in ICU during mechanical ventilation

Noninvasive Ventilation in Patients With ARF and Do-Not-Intubate and Comfort-Measures-Only Orders

A large proportion of patients with do-not-intubate orders who received noninvasive ventilation survived to hospital discharge and at 1 year, with limited data showing no decrease in quality of life in survivors. Provision... read more

Noninvasive Ventilation in Patients With ARF and Do-Not-Intubate and Comfort-Measures-Only Orders

Dysphagia – A Common, Transient Symptom in Critical Illness Polyneuropathy

Dysphagia is frequent among patients with critical illness polyneuropathy treated in the ICU. Old age, chronic obstructive pulmonary disease, the mode of mechanical ventilation, the prevalence of tracheal tubes, and behavioral... read more

Dysphagia – A Common, Transient Symptom in Critical Illness Polyneuropathy

C. difficile risk raised by using same hospital bed as antibiotic-treated patient

Antibiotic use is associated with greater risk of Clostridium difficile infection, but according to a new study, you do not necessarily need to take antibiotics for them to pose such a risk. Researchers suggest just using... read more

C. difficile risk raised by using same hospital bed as antibiotic-treated patient

Mitochondrial Function in Sepsis

The authors were tasked with developing five specific questions regarding mitochondrial function in sepsis within the context of the Acute Dialysis Quality Initiative 14 (ADQI XIV) meeting held in Bogotá, Colombia, in late... read more

Mitochondrial Function in Sepsis

Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric ARDS Mortality

Patients with PARDS managed with lower PEEP relative to FiO2 than recommended by the ARDSNet model had higher mortality. Clinical trials targeting PEEP management in PARDS are needed. This was a multicenter, retrospective... read more

Positive End-Expiratory Pressure Lower Than the ARDS Network Protocol Is Associated with Higher Pediatric ARDS Mortality

Sodium Bicarbonate Therapy for Patients with Severe Metabolic Acidaemia in the ICU

In patients with severe metabolic acidaemia, sodium bicarbonate had no effect on the primary composite outcome. However, sodium bicarbonate decreased the primary composite outcome and day 28 mortality in the a-priori defined... read more

Sodium Bicarbonate Therapy for Patients with Severe Metabolic Acidaemia in the ICU