Hypertension and Prehypertension Underdiagnosed, Undertreated in U.S. Children

Hypertension and prehypertension in children often go undiagnosed, according to a new study published in Pediatrics. The study focused on children with abnormal blood pressures across the United States.... read more

Hypertension and Prehypertension Underdiagnosed, Undertreated in U.S. Children

Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Ingredient in aspirin combined with popular diabetes drug can turn off faulty protein that plays a key role in inflammatory diseases, such as rheumatoid arthritis. ... read more

Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Sepsis National Hospital Inpatient Quality Measure

The Center for Medicare and Medicaid Services adopted the Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) performance measure to the Hospital Inpatient Quality Reporting Program in July 2015 to help address the... read more

Sepsis National Hospital Inpatient Quality Measure

Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI

Substantial variation was found regarding monitoring and treatment policies in patients with Traumatic Brain Injury (TBI) and intracranial hypertension. The results of this survey indicate a lack of consensus between European... read more

Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI

The Overlaps of Asthma or COPD with OSA

Asthma, chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are the most common respiratory disorders worldwide. Given demographic and environmental changes, prevalence for each is likely to increase. Some... read more

The Overlaps of Asthma or COPD with OSA

Examining When to Provide Pain Management for Patients

Sometimes a lack of pain medication is the patient's best form of treatment. Eradicating pain has been a focus of medicine throughout history, from the early use of cocaine to the current use of fentanyl. As a prehospital... read more

Examining When to Provide Pain Management for Patients

CDC Urges Early Recognition, Prompt Treatment of Sepsis

The Centers for Disease Control and Prevention today launched Get Ahead of Sepsis, an educational initiative to protect Americans from the devastating effects of sepsis. This initiative emphasizes the importance of early... read more

CDC Urges Early Recognition, Prompt Treatment of Sepsis

A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation

Oral anticoagulation is underused in patients with atrial fibrillation. We assessed the impact of a multifaceted educational intervention, versus usual care, on oral anticoagulant use in patients with atrial fibrillation.... read more

A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation

FDA Approves ‘living drug’ to Cure Cancer

FDA has approved the first treatment to redesign immune system so it attacks the cancer cells. Kymriah therapy, which leaves 83% of people free of a type of blood cancer, costs about $475,000 and was developed by Novartis.... read more

FDA Approves ‘living drug’ to Cure Cancer

Individualizing Thresholds of Cerebral Perfusion Pressure Using Estimated Limits of Autoregulation

Individualized autoregulation-guided cerebral perfusion pressure management may be a plausible alternative to fixed cerebral perfusion pressure threshold management in severe traumatic brain injury patients. Prospective randomized... read more

Individualizing Thresholds of Cerebral Perfusion Pressure Using Estimated Limits of Autoregulation

Antibiotic Guidelines Improve Prescription Practices for Vulnerable Infants

Yale University School of Medicine neonatal intensive care unit (NICU) significantly reduced the number of cases of late-onset sepsis, a leading cause of death among pre-term infants, by implementing guidelines designed to... read more

Antibiotic Guidelines Improve Prescription Practices for Vulnerable Infants

Incidence, Prevalence, and Management of MRSA Bacteremia Across Patient Populations

Methicillin-resistant Staphylococcus aureus (MRSA) infection is still a major global healthcare problem. Of concern is S. aureus bacteremia, which exhibits high rates of morbidity and mortality and can cause metastatic or... read more

Incidence, Prevalence, and Management of MRSA Bacteremia Across Patient Populations

Successful Long-Term ECMO for Invasive Pulmonary Aspergillosis

Extracorporeal membrane oxygenation is an established life-saving procedure for severe acute respiratory failure due to various causes. Long-term extracorporeal membrane oxygenation might be considered if the primary causes... read more

Successful Long-Term ECMO for Invasive Pulmonary Aspergillosis

External Validity of Electronic Sniffers for Automated Recognition of ARDS

Automated electronic sniffers may be useful for early detection of acute respiratory distress syndrome (ARDS) for institution of treatment or clinical trial screening. Published electronic sniffer algorithms for ARDS may... read more

External Validity of Electronic Sniffers for Automated Recognition of ARDS

Clinical Impact of COPD on Non-cystic Fibrosis Bronchiectasis

Clinical impact of chronic obstructive pulmonary disease on non-cystic fibrosis bronchiectasis. A study on 1,790 patients from the Spanish Bronchiectasis Historical Registry. Patients with BE related to COPD have the same... read more

Clinical Impact of COPD on Non-cystic Fibrosis Bronchiectasis

Effect of Obstructive Sleep Apnea Treatment on Renal Function in Patients with Cardiovascular Disease

Obstructive sleep apnea (OSA) is associated with impaired renal function, but uncertainty exists over whether OSA treatment can influence renal outcomes. Objectives: To determine the effects of continuous positive airway... read more

Effect of Obstructive Sleep Apnea Treatment on Renal Function in Patients with Cardiovascular Disease

When Evidence Says No, but Doctors Say Yes

Long after research contradicts common medical practices, patients continue to demand them and physicians continue to deliver. The result is an epidemic of unnecessary and unhelpful treatments.... read more

Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock

Several studies have reported a survival benefit for polymyxin B hemoperfusion treatment in patients with severe sepsis and septic shock. However, recently, a propensity-matched analysis and a randomized controlled trial... read more

Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock

New Diagnostic Tests: More Harm Than Good

Although new diagnostics may advance the time of diagnoses in selected patients, they will increase the frequency of false alarms, overdiagnosis, and overtreatment in others. Bjorn Hofmann and H. Gilbert Welch explain how... read more

New Diagnostic Tests: More Harm Than Good

In Treating Sepsis, Questions About Timing and Mandates

The question of whether Rory's Regulations save lives isn’t asked or answered in the recent study. Sepsis deaths were already decreasing in the United States before the mandate, and determining its contribution to... read more

In Treating Sepsis, Questions About Timing and Mandates

How to Remove the Grey Area Between VAP and VAT?

We read with great interest the study performed by Paula Ramirez and colleagues. The study included 71 patients with ventilator-associated pneumonia (VAP) and the authors coined a new term called "gradual VAP".... read more

How to Remove the Grey Area Between VAP and VAT?