Tag: trial
ICDs appear not to improve overall survival in non-ischemic systolic HF
This paper reports the findings of the DANISH study, a multicenter, unblinded, randomized, controlled trial to compare outcomes in patients with non-ischemic systolic heart failure who received cardiac resynchronization therapy... read more
Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke
Compared to patients treated with medical therapy alone, patients with an ischemic stroke undergoing endovascular thrombectomy combined with medical therapy had lower rates of disability 3 months after their stroke.... read more
Beta-Lactam Infusion in Severe Sepsis (BLISS)
Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis.... read more
FDA approves automated insulin delivery device for type 1 diabetes
The Food and Drug Administration (FDA) has approved a device that automatically monitors blood glucose levels and delivers insulin when appropriate, for people aged 14 years and older who have type 1 diabetes.... read more
When Your Doctor Is on a 30-Hour Shift
A new program has medical residents working for up to 30 hours without sleep in ICUs - putting patients in danger of hospital errors.... read more
Dramatic remissions seen in immunotherapy trial of blood cancer patients
Many patients with advanced blood cancers who are receiving experimental, "living" immunotherapy as part of a clinical trial are experiencing sustained remissions, according to preliminary results of the ongoing... read more
Researchers hope to speed recovery of critically ill patients with bikes in their beds
An experiment in the intensive care unit of The Ottawa Hospital aims to test whether critically ill patients can get back on their feet faster by cycling in bed. As part of the randomized clinical.... read more
New Research Shows NEPHROCHECK Test Predicts Acute Kidney Injury Risk For Transaortic Valve Implant Patients
Astute Medical, Inc., developer of biomarkers for better healthcare, today said that newly published findings show that the Company's NEPHROCHECK Test may help physicians identify risk of a serious complication in patients... read more
Signs of Cardioprotection Seen in Acute STEMI Patients Receiving IV Beta-blocker Post-PCI
Patients with STEMI who receive IV infusion of the beta-blocker esmolol within 60 minutes after successful PCI tend to release smaller amounts of cardiac biomarkers than those given placebo, researchers of a single-center,... read more
Effect of atorvastatin on the incidence of acute kidney injury following valvular heart surgery
Statins, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors have the potential to reduce acute kidney injury (AKI) after cardiac surgery through their pleiotropic properties. Here we studied the preventive... read more
Catheter ablation more effective than antiarrythmic escalation
Catheter ablation was found to be more effective than escalated antiarrhythmic drug (AAD) therapy at treating patients with ischemic cardiomyopathy and an implantable cardioverter-defibrillator (ICD) who had ventricular tachycardia... read more
Non-addictive Painkiller Shows Promise in Animal Trials
Preliminary research in monkeys suggests that a new medication might be able to provide pain relief similar to opioid drugs such as OxyContin, but without the same potential for addiction or serious side effects.... read more
What did the ALPS trial results really show?
The trial pitted amiodarone against lidocaine with a saline control group for the termination of shock-resistant ventricular tachycardia and ventricular fibrillation... read more
Antibiotics: resist the resistance
European Pharmaceutical Review caught up with Destiny Pharma’s CEO, Dr Love, for an interview about the threat of bacterial resistance to antibiotics...... read more
Review: Stem Cell Tx for Heart Failure Not Ready Yet
Heterogeneity in methods for trials of stem cell therapies for heart failure are a big reason for the inconsistent results seen to date, a review article suggested.... read more
Artificial pancreas could save lives
An Asheville doctor-and-son team have an idea they say could save at least 100,000 lives a year. Leon and Jeremy DeJournett have patented an artificial pancreas, a system that uses a form of artificial intelligence to ensure... read more
Driving Risk Factors Behind Ventilator-Associated Pneumonia
Ventilators that help patients breathe can be life-saving devices; however, they also have the power to cause deadly ventilator-associated pneumonia (VAP).... read more
Earlier Renal Replacement Therapy for AKI? Not So Fast, Says Dr Berns
The AKIKI study was published in the New England Journal of Medicine; ELAIN was published in JAMA. If you have not read them, you should, if for no other reason than that your colleagues are likely to ask about them.... read more
Digital PCR Detection of Cancer Mutations from Liquid Biopsies
Guest Editor, Randall Evans, Ph.D of Biodesix, discusses the recent success of a clinical trial of a diagnostic blood test.... read more
Is Timing Really Everything With RRT?
For years we have been told that early interventions result in better patient outcomes. Early cardiac catheterization results in more preserved myocardial function.... read more
Hamilton researchers conduct ground-breaking new trial on pediatric fecal transplant for IBD
Hamilton researchers are conducting a ground-breaking new trial looking at fecal transplants to help treat inflammatory bowel disease (IBD) in children.... read more
