Pathophysiology, echocardiographic evaluation, biomarker findings, and prognostic implications of septic cardiomyopathy

Pathophysiology, echocardiographic evaluation, biomarker findings, and prognostic implications of septic cardiomyopathy

As a result of conflicting data, echocardiographic measures of left ventricular (systolic or diastolic) or right ventricular function cannot currently provide reliable prognostic information in patients with sepsis. Natriuretic... read more

Overuse of troponin? A comprehensive evaluation of testing in a large hospital system

Overuse of troponin? A comprehensive evaluation of testing in a large hospital system

Troponin assays are integral to the diagnosis of acute myocardial infarction (AMI), but there is concern that testing is over utilized and may not conform to published guidelines. We reviewed all testing performed at 14 hospitals... read more

High-Sensitivity Troponins and Outcomes After Myocardial Infarction

High-Sensitivity Troponins and Outcomes After Myocardial Infarction

An excellent report from Kai Eggers et al in Sweden on impact of introducing high-sensitivity cardiac troponins in 87,879 patients with myocardial infarction. In a nationwide cohort study on patients with a first MI, the... read more

Does Preoperative Troponin Level Impact Outcomes Following Coronary Artery Bypass Grafting?

Does Preoperative Troponin Level Impact Outcomes Following Coronary Artery Bypass Grafting?

As a marker of myocardial injury, troponin level correlates with adverse outcomes following myocardial infarction (MI). We hypothesized that patients with higher preoperative troponin level would have increased morbidity... read more

Early Troponin I in Critical Illness and its Association with Hospital Mortality

Early Troponin I in Critical Illness and its Association with Hospital Mortality

TnI is an independent predictor of hospital mortality and correlates most highly with the APS component of APACHE II. It does not improve risk prediction. We would not advocate the adoption of routine troponin analysis on... read more

A Brief Review of Troponin Testing for Clinicians

A Brief Review of Troponin Testing for Clinicians

Current American College of Cardiology and American Heart Association guidelines state that troponin is the preferred biomarker for diagnosing acute myocardial infarction (MI). Troponin T (TnT) and I molecules have amino... read more

1-Hour AMI Rule; Early Steroids in Kawasaki Disease; The Gut in PAD

1-Hour AMI Rule; Early Steroids in Kawasaki Disease; The Gut in PAD

Sensitivity of the European Society of Cardiology's 1-hour algorithm for assessing acute MI with high-sensitivity cardiac troponin may be insufficient for some ED physicians to confidently send patients home.... read more