Influenza and COVID-19 Vaccination Rates Among Children Receiving Long-Term Ventilation

Children with tracheostomy and HV are at high risk of morbidity and mortality from viral ARIs. Among MyTRaCh enrollees, we found significant discrepancy between influenza and COVID-19 vaccination status. Compared with... read more

How does high fowlers position help with ventilation?

The High Fowler's position, characterized by an inclination of 60-90 degrees, significantly enhances ventilation by optimizing lung expansion and improving respiratory mechanics. This position is particularly beneficial for... read more

COVID-19 ARDS Patients vs. Patients with ARDS

Ventilation management may differ between COVID–19 ARDS (COVID–ARDS) patients and patients with pre–COVID ARDS (CLASSIC–ARDS); it is uncertain whether associations of ventilation management with outcomes for CLASSIC–ARDS... read more

Tracheal Intubation in Critically Ill Adults with a Physiologically Difficult Airway

Using a Delphi method, agreement among a panel of international experts was reached for 53 statements providing guidance to clinicians worldwide on safe tracheal intubation practices in patients with a physiologically difficult... read more

Basics of Mechanical Ventilation

Basics of Mechanical Ventilation

This book is a practical and easily understandable guide for mechanical ventilation. With a focus on the basics, this text begins with a detailed account of the mechanisms of spontaneous breathing as a reference point to... read more

Ultrafast Cooling With Total Liquid Ventilation Mitigates Early Inflammatory Response

Ultrafast cooling with TLV mitigates neuroinflammation and attenuates acute brain lesions in the early phase following resuscitation in large animals subjected to cardiac arrest (CA). Brain injury is one of the most serious... read more

Pitfalls in the Management of Mechanical Ventilation: ARDS and Hypermetabolic States

Mechanical Ventilation (MV) is an invaluable, lifesaving therapy for patients with acute respiratory failure, but it must be individualized for each specific underlying physiologic derangement to maximize benefits and minimize... read more

Antifungal Prophylaxis of COVID-19 Associated Pulmonary Aspergillosis in Ventilated Patients

This study investigated the impact of POSA prophylaxis on risk of CAPA development in mechanically ventilated COVID-19 patients receiving corticosteroids. We observed a significant variation in CAPA incidence rates among... read more

High-flow Nasal Cannula Oxygen vs. NIV in AHF-related ARF

In this pilot study, we did not observe a statistically significant difference in changes in respiratory rate among patients with acute respiratory failure (ARF) due to acute heart failure (AHF) and managed with high-flow... read more

Weaning From Mechanical Ventilation in ICUs Across 50 Countries

Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients... read more

Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients

Among adults receiving mechanical ventilation in the ICU, adding early in-bed Cycling to usual physiotherapy did not improve physical function at 3 days after discharge from the ICU compared with Usual physiotherapy alone.... read more

Mechanical Ventilation in the ICU: A New Approach and Treatment

Mechanical Ventilation in the ICU: A New Approach and Treatment

In the present book, a broad description of the processes carried out in patients with mechanical ventilation in the ICU is made. It covers from an overview of mechanical ventilation and some of its history to the processes... read more

Noninvasive Ventilation for Preoxygenation during Emergency Intubation

Among critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation resulted in a lower incidence of hypoxemia during intubation than preoxygenation with an oxygen mask. Among the 1,301... read more

The role of pleural pressure and airway closure during mechanical ventilation

The role of pleural pressure and airway closure during mechanical ventilation

Related to our paper, Van Egmond et al. highlighted key physiological concepts we must be aware of. We believe, however, that the described physiological com-plexity has limited impact on the daily use of esophageal pressure... read more

Two weaning strategies for NIV in COPD patients with ARF

Two weaning strategies for NIV in COPD patients with ARF

Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

We present a case of 43-year-old male patient with broadly by Omalizumab, Mepolizumab and Benralizumab pretreated allergic asthma, who suffered a near fatal exacerbation, triggered by an influenza A infection. Due to... read more