COVID-19 ARDS Patients vs. Patients with ARDS

Ventilation management may differ between COVID–19 ARDS (COVID–ARDS) patients and patients with pre–COVID ARDS (CLASSIC–ARDS); it is uncertain whether associations of ventilation management with outcomes for CLASSIC–ARDS... read more

Tracheal Intubation in Critically Ill Adults with a Physiologically Difficult Airway

Using a Delphi method, agreement among a panel of international experts was reached for 53 statements providing guidance to clinicians worldwide on safe tracheal intubation practices in patients with a physiologically difficult... read more

Ultrafast Cooling With Total Liquid Ventilation Mitigates Early Inflammatory Response

Ultrafast cooling with TLV mitigates neuroinflammation and attenuates acute brain lesions in the early phase following resuscitation in large animals subjected to cardiac arrest (CA). Brain injury is one of the most serious... read more

Pitfalls in the Management of Mechanical Ventilation: ARDS and Hypermetabolic States

Mechanical Ventilation (MV) is an invaluable, lifesaving therapy for patients with acute respiratory failure, but it must be individualized for each specific underlying physiologic derangement to maximize benefits and minimize... read more

Antifungal Prophylaxis of COVID-19 Associated Pulmonary Aspergillosis in Ventilated Patients

This study investigated the impact of POSA prophylaxis on risk of CAPA development in mechanically ventilated COVID-19 patients receiving corticosteroids. We observed a significant variation in CAPA incidence rates among... read more

High-flow Nasal Cannula Oxygen vs. NIV in AHF-related ARF

In this pilot study, we did not observe a statistically significant difference in changes in respiratory rate among patients with acute respiratory failure (ARF) due to acute heart failure (AHF) and managed with high-flow... read more

Weaning From Mechanical Ventilation in ICUs Across 50 Countries

Current management practices and outcomes in weaning from invasive mechanical ventilation are poorly understood. We aimed to describe the epidemiology, management, timings, risk for failure, and outcomes of weaning in patients... read more

Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients

Among adults receiving mechanical ventilation in the ICU, adding early in-bed Cycling to usual physiotherapy did not improve physical function at 3 days after discharge from the ICU compared with Usual physiotherapy alone.... read more

Noninvasive Ventilation for Preoxygenation during Emergency Intubation

Among critically ill adults undergoing tracheal intubation, preoxygenation with noninvasive ventilation resulted in a lower incidence of hypoxemia during intubation than preoxygenation with an oxygen mask. Among the 1,301... read more

The role of pleural pressure and airway closure during mechanical ventilation

Related to our paper, Van Egmond et al. highlighted key physiological concepts we must be aware of. We believe, however, that the described physiological com-plexity has limited impact on the daily use of esophageal pressure... read more

The role of pleural pressure and airway closure during mechanical ventilation

Two weaning strategies for NIV in COPD patients with ARF

Non-Invasive Ventilation (NIV) is a crucial therapy for managing acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) with hypercapnic respiratory failure. Research has shown that NIV can decrease the rate... read more

Two weaning strategies for NIV in COPD patients with ARF

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

This quality improvement (QI) project aimed to standardize and re-establish RT-driven protocol for screening patients for SBT readiness and administering SBTs to appropriate patients. Endotracheally intubated and mechanically... read more

Improving Spontaneous Breathing Trials With a Respiratory Therapist-Driven Protocol

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

We present a case of 43-year-old male patient with broadly by Omalizumab, Mepolizumab and Benralizumab pretreated allergic asthma, who suffered a near fatal exacerbation, triggered by an influenza A infection. Due to... read more

Tezepelumab in a case of severe asthma exacerbation and influenza-pneumonia on VV-ECMO

Prone Positioning During ECMO for Severe ARDS

The ongoing debate on optimal extracorporeal membrane oxygenation (ECMO) care emphasizes the need for rigorous investigation, acknowledging the value of observational data in routine The PRONECMO study, with its pragmatic... read more

Prone Positioning During ECMO for Severe ARDS

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

This book describes the issues and challenges that clinicians encountered in the management of older critically ill patients during the COVID-19 pandemic, and offers practical information on how to manage them. Older... read more

COVID-19 Airway Management and Ventilation Strategy for Critically Ill Older Patients

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Delivery of prehospital emergency anesthesia (PHEA) to seriously injured trauma patients risks hemodynamic fluctuation. In adult trauma patients undergoing PHEA, 11.9% of patients experienced post-PHEA critical hypertension.... read more

Critical Hypertension in Trauma Patients Following Prehospital Emergency Anesthesia

Intravenous Vitamin C for COVID-19 Patients

In hospitalized patients with COVID-19, vitamin C had low probability of improving the primary composite outcome of organ support–free days and hospital survival. Enrollment was terminated after statistical triggers... read more

Intravenous Vitamin C for COVID-19 Patients

Effect of Mechanical Ventilation Under Intubation on Respiratory Tract Change of Bacterial Count

Mechanical ventilation under intubation may cause dysregulation of lower respiratory microbiota in rats. The most common 'second strike' in mechanically ventilated patients is a pulmonary infection caused by the ease with... read more

Effect of Mechanical Ventilation Under Intubation on Respiratory Tract Change of Bacterial Count

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange vs. Conventional Facemask Breathing for Preoxygenation During Rapid Sequence Induction

Transnasal humidified rapid-insufflation ventilatory exchange (THRIVE), if used for pre-oxygenation and apnoeic oxygenation, has the propensity to extend the safe apnoea time and thereby decrease the incidence of desaturation... read more

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange vs. Conventional Facemask Breathing for Preoxygenation During Rapid Sequence Induction

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

The study revealed that the utilization of non-ICU sophisticated ventilators was linked to a higher mortality rate when compared to standard ICU ventilators in COVID-19 patients with ARDS. However, given the shortage and... read more

1-year Survival Rate of COVID-19 Infected Patients with ARDS Based on Ventilator Types

Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

This book is an introduction to a comprehensive analysis of recent advances and clinical research in noninvasive mechanical ventilation (NIV) in Pulmonary, Critical Care, and Sleep Medicine. The objective of the book is to... read more

Noninvasive Ventilation in Sleep Medicine and Pulmonary Critical Care

ReddyPort Non-Invasive Ventilation Device Cleared By FDA

ReddyPort announced today that the US Food and Drug Administration (FDA) granted 510(k) premarket clearance for the ReddyPort elbow device used in non-invasive ventilation (NIV). "ReddyPort's patented elbow is central... read more

ReddyPort Non-Invasive Ventilation Device Cleared By FDA