Assessment of Respiratory Muscles, Lung Parenchyma, and Cardiac Function by Ultrasound for Predicting Weaning Failure in Critically Ill Adults

onlinelibrary.wiley.com October 15, 2024

Parasternal intercostal muscle thickening fraction (PMTF) has good discriminatory power to predict weaning outcomes (area under the receiver operating characteristic curve: 0.74 [0.59–0.88]). Pre-SBT PMTF had similar power as DTF to predict weaning failure.

This prospective observational study conducted in a mixed medical-surgical intensive care unit, included 60 adult patients who were eligible for a spontaneous breathing trial (SBT) after being invasively mechanically ventilated for more than 48 hours. Ultrasound of respiratory muscles, lung parenchyma, and echocardiographic assessment were performed before and after 120 minutes of SBT.