The COVID-19 pandemic has caused intensive care units (ICUs) to reach capacities requiring triage. A tool to predict mortality risk in ventilated patients with COVID-19 could inform decision-making and resource allocation, and allow population-level comparisons across institutions.

In this analysis, we derived and internally validated a pragmatic, dynamic, clinical score that facilitates accurate prediction of mortality in ventilated patients with COVID-19.

This tool may provide additional prognostic information allowing improved local resource planning and more accurate comparisons across patients treated with different therapies or in different ICUs.

Future work is required to validate our results in other cohorts.

127 patients were eligible for inclusion.

Median ICU length of stay was 26.9 days.

Overall mortality was 42%.

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