This case report illustrates the ability of the novel biomarker pancreatic stone protein (PSP) concentrations to act as a warning sign, allowing the early identification of intra-abdominal infection and post-operative peritonitis episodes, even prior to their clinical diagnosis (pre-symptomatic diagnosis of sepsis).

PSP facilitated prompt surgery in this case report.

Further studies can help to fully understand the role of PSP in intra-abdominal infections and post-operative peritonitis.

The diagnosis of intra-abdominal infection and post-operative peritonitis based on clinical examination, biomarkers and radiological signs, should be made as early as possible to improve outcomes and decrease mortality through early and optimal source control, adequate surgery and appropriate antibiotic therapy.

Read More