Among critically ill patients in the ICU, a nurse-led preventive, complex psychological intervention did not significantly reduce patient-reported Posttraumatic Stress Disorder (PTSD) symptom severity at 6 months. These findings do not support the use of this psychological intervention.

1,458 enrolled patients completed the study and were included in the final analysis.

The primary clinical outcome was PTSD symptom severity among survivors at 6 months measured using the PTSD Symptom Scale-Self-Report questionnaire.

24 ICUs were randomized 1:1 to the intervention or control group.

Intervention ICUs delivered usual care during a baseline period followed by an intervention period.

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