No differences found in pulmonary function in patients reversed with sugammadex or neostigmine in a high-risk population.

126 patients were included in the main analysis.

In the neostigmine group (n = 64), mean (95% confidence interval [95% CI]) reduction in FVC after one hour was 0.5 (0.4 to 0.6) L.

In the sugammadex group (n = 62), the mean (95% CI) reduction in FVC during the first hour was 0.5 (95% CI, 0.3 to 0.6) L.

39% of patients in the neostigmine group and 29% in the sugammadex group had visible atelectasis.

136 adults scheduled for major abdominal surgery under combined general and epidural anesthesia were randomly allocated to receive 40 µg of neostigmine or 4 mg·kg−1 of sugammadex to reverse neuromuscular block.

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