Chronic obstructive pulmonary disease (COPD) is a leading cause of global morbidity and death. The blood urea nitrogen-to-creatinine ratio (BCR) is recognized as a crucial marker to assess renal function and cardiovascular risk. Nevertheless, the effects of BCR on COPD patients suffering comorbid congestive heart failure (CHF) is not clarified. This study aims to elucidate the association between BCR and CHF risk in the COPD population.

This study based on the MIMIC-IV database presents clinical evidence linking BCR to the risk of CHF and IHM in critically ill COPD people.

BCR is an independent risk factor for CHF in the COPD population, with high BCR significantly related to poor prognosis, indicating that BCR can serve as an important prognostic marker for COPD patients.

Therefore, clinical practice should emphasize monitoring BCR in COPD patients to note high-risk individuals early and offer timely interventions.

These findings offer valuable clinical guidance for individualized management of COPD patients and contribute to understanding the potential pathological mechanisms leading to CHF in this population, providing a basis for developing more effective intervention strategies.

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