Contrary to previously published data, our analysis did not demonstrate an association between eosinopenia and increased mortality risk in hospitalized patients with community-acquired pneumonia (CAP), highlighting the complexity of CAP prognosis.

Further investigations and comprehensive approaches are warranted to elucidate the intricate interplay of variables contributing to the prognosis of hospitalized CAP patients.

The primary outcome was in-hospital mortality.

Secondary outcomes included hospital length of stay, intensive care unit admission, need for noninvasive ventilation and invasive mechanical ventilation support, need for vasopressor support, and 30-day mortality.

In-hospital mortality was defined as all-cause mortality occurring during the hospital stay, while 30-day mortality encompassed all-cause mortality within 30 days from admission.

Length of hospital stay was defined as the duration of each patient’s hospitalization from admission to discharge.

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