Fever is Associated with Reduced Mortality in ICU Patients with Sepsis
nature.comTo evaluate the association of body temperature with mortality in septic patients admitted to the ICU from the ward.
In addition, we intend to investigate whether the timing of antibiotic administration was different between febrile and afebrile patients and whether this difference contributed to mortality.
This is a retrospective cohort study that included sepsis patients admitted to the ICU from the ward between July 2017 and July 2019.
Antibiotic administration was defined as the initiation of antimicrobial treatment or the expansion of the antimicrobial spectrum within 48 h prior to admission to the ICU.
Regarding vital signs, the most altered vital sign in the 48 h prior to admission to the ICU was considered.
208 patients were included in the final analysis.
Antibiotic administration occurred earlier in patients with fever than in patients without fever.
Antibiotic administration occurred before admission to the ICU in 27 (90.0%) patients with fever and in 101 (64.7%) patients without fever.