A witty, irreverent tour of history’s worst plagues―from the Antonine Plague, to leprosy, to polio―and a celebration of the heroes who fought them.

In 1518, in a small town in Alsace, Frau Troffea began dancing and didn’t stop. She danced until she was carried away six days later, and soon thirty-four more villagers joined her. Then more. In a month more than 400 people had been stricken by the mysterious dancing plague. In late-seventeenth-century England an eccentric gentleman founded the No Nose Club in his gracious townhome―a social club for those who had lost their noses, and other body parts, to the plague of syphilis for which there was then no cure. And in turn-of-the-century New York, an Irish cook caused two lethal outbreaks of typhoid fever, a case that transformed her into the notorious Typhoid Mary.

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