Hemoglobin Glycation Index vs. Adverse Outcomes in Critically Ill Patients with Myocardial Infarction

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Based on the MIMIC-IV database, this study found that lower HGI is significantly associated with an increased risk of short-, mid- and long-term all-cause mortality in critically ill myocardial infarction (MI) patients. As a potential clinical marker for adverse outcomes, hemoglobin glycation index (HGI), may help identify high-risk individuals early and guide clinical management to improve patient prognosis.

Based on the MIMIC-IV database, this study investigated the association between the HGI and adverse outcomes in critically ill MI patients.

The results indicated that low HGI was significantly associated with an increased risk of all-cause mortality at short-, mid-, and long-term follow-ups.

This association remained significant even after adjusting for demographics, vital signs, laboratory tests, comorbidities, clinical scores, and medication usage.

Furthermore, patients in the low-HGI group had higher hospital mortality, a greater incidence of severe AKI, and longer ICU stays.

These findings underscore the clinical value of HGI as a prognostic marker, supporting early identification and targeted intervention for high-risk MI patients.

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