In patients with severe polytrauma, heparin-binding protein may predict bacterial infection. Combining heparin-binding protein, PCT, and neutrophils may improve bacterial infection prediction. HBP provides a referenceable test for early disease assessment.

This is a prospective single-center study.

Patients with polytrauma in the emergency intensive care unit were selected for the study, and plasma heparin-binding protein concentrations and other laboratory parameters were measured within 48 hours of admission to the hospital.

97 patients with polytrauma were included in the study, 43 with bacterial infection and 54 without infection.

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