A high-flow nasal cannula (HFNC) is a high-flow oxygen supply device developed in recent years and is increasingly being used to treat acute hypoxemic respiratory failure (AHRF) in intensive care unit (ICU). Patients with pre-existing chronic lung disease (CLD) often develop AHRF and require ICU admission. HFNC therapy is also used for these patients in clinical practice, although few studies have examined its efficacy. We investigated the efficacy of HFNC therapy for the treatment of AHRF in patients with pre-existing CLD.

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