Hospitals with higher risk- and reliability-adjusted 30-day mortality have a higher probability of developing persistent critical illness. Understanding the drivers of this variation may identify modifiable factors contributing to the development of persistent critical illness.

In the analysis of 100 hospitals which encompassed 153,512 hospitalizations, 4.9% developed persistent critical illness.

There was variation in the development of persistent critical illness despite controlling for patient characteristics.

Hospitals with higher risk- and reliability-adjusted 30-day mortality had higher probabilities of developing persistent critical illness (predicted probability: 0.057, 95% CI 0.051–0.063, p < 0.01) compared to those with lower risk- and reliability-adjusted 30-day mortality.

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