A high proportion of ITP patients suffered from metabolic disorders, especially hyperlipidemia. Patients with hyperlipidemia may have more severe bleeding symptoms and worse responses to ITP treatments.

Statin may help relieve ITP bleeding symptoms and improve ITP treatment.

We found a high proportion of ITP patients suffered from hyperlipidemia, and other metabolic diseases including cardiovascular or cerebral atherosclerosis or infarction, hypertension, and type 2 diabetes.

Hyperlipidemia was associated with severe bleeding and treatment refractoriness in ITP.

Statins could alleviate thrombocytopenia and bleeding severity, and facilitate ITP treatment, while improving hyperlipidemia in ITP patients.

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