ICU-AW in Cardiogenic Shock Patients Requiring Mechanical Circulatory Support

nature.com January 29, 2025

This study provides insights into the characteristics of intensive care unit-acquired weakness (ICU-AW) in patients with Cardiogenic Shock (CS) requiring mechanical circulatory support (MCS).

ICU-AW frequently occurred in patients with CS using MCS, indicating the significance of recognizing and managing this complication for those patients.

While the MRC score improved over 6 months, there was evidence of a prolonged decline in physical function-related QOL and exercise capacity, indicating the need for long-term monitoring and interventions to address functional impairments.

Moreover, we indicates that serum IL-15 may be a valuable predictive biomarker of ICU-AW, which may be useful for early identification of ICU-AW in patients with CS using MCS.

A total of 47 patients with CS who underwent MCS between April 2020 and June 2022 were enrolled.