Intraoperative oxidative stress is associated with postoperative delirium in ICU patients after cardiac surgery, a study has found. Researchers from Vanderbilt University Medical Center, in Nashville, Tenn., came to this conclusion after they found plasma concentrations of F2-isoprostanes and isofurans, markers of oxidative damage, are associated with delirium. They measured plasma concentrations of F2-isoprostanes and isofurans throughout the surgical period in 385 patients undergoing cardiac surgery.

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