Lactate is an important parameter for monitoring tissue perfusion at present. Lactate kinetics are particularly important to evaluate the response of ICU patients.

Therefore, lactate can be the starting point for resuscitation, and monitored during the process of resuscitation to assess whether tissue perfusion is being adequately restored.

A large proportion of patients in the ScvO2 group (approximately 69% of the patients in our study) could not receive future resuscitation according to the protocol, even though the average enrollment lactate levels were around 5.5 mmol/L.

However, the patients with high lactate levels could still enter the lactate kinetics group.

An optimal resuscitation target should be able to generate sufficient driving force for the specific clinical treatment so that it can better guide the clinical therapy.

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