The nearly 75% mortality four years after diagnosis indicates that changes are needed both in the acute treatment of patients with sepsis and in their multi-sector long-term care. The applicability of these findings may be limited by their having been obtained in a single center.

1,975 patients with sepsis or septic shock were included.

The mean time of observation was 730 days.

For 96.4% of the queries to the general practitioners, information on long-term survival was available.

Mortality in the intensive care unit was 34%, and in-hospital mortality was 45%.

The overall mortality six months after diagnosis was 59%, the overall mortality 48 months after diagnosis was 74%.

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