Milrinone vs. Dobutamine in the Treatment of Cardiogenic Shock
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In patients with cardiogenic shock, no significant difference between Milrinone and Dobutamine was found with respect to the primary composite outcome or important secondary outcomes.
A total of 192 participants (96 in each group) were enrolled.
The treatment groups did not differ significantly with respect to the primary outcome; a primary outcome event occurred in 47 participants (49%) in the Milrinone group and in 52 participants (54%) in the Dobutamine group.
There were also no significant differences between the groups with respect to secondary outcomes, including in-hospital death, resuscitated cardiac arrest, receipt of mechanical circulatory support, or initiation of renal replacement therapy.