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No difference between placebo, amitriptyline and topiramate in reducing pediatric migraine

2minutemedicine.com January 16, 2017

In this study, no significant intergroup differences between amitriptyline, topiramate and placebo for reduction in total number of headache days was observed. Amitriptyline and topiramate were associated with significantly higher rates of adverse side effects compared to placebo.

placebo research study trial

Early Antiviral Use and Supplemental Oxygen Decrease the Risk of Secondary Bacterial Infections

Cardiac Damage in Patients Infected with Different COVID-19 Variants of Concern

Long-term Prevalence of PTSD Symptom in Family Members of Severe COVID-19 Patients

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

A Perspective on Post-Cardiac Arrest Syndrome

Sepsis: Methods and Protocols

The Clinical Diagnosis and Treatment for New Coronavirus Pneumonia

The Real Doctor Will See You Shortly: A Physician’s First Year

Perioperative Fluid Management

Fluid, Electrolyte and Acid-Base Disorders

Case Studies in Adult Intensive Care Medicine

Hemodynamic Monitoring Using Echocardiography in the Critically Ill

Bedside Procedures in the ICU

Severe Trauma and Sepsis: Organ Damage and Tissue Repair

Evidence-Based Critical Care: A Case Study Approach

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

ECMO in the Adult Patient (Core Critical Care)

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management