Outcomes and Characteristics of Cardiac Arrest in Children with Pulmonary Hypertension
sciencedirect.comIn this prospective study of children who received CPR in intensive care units, a pre-existing diagnosis pulmonary hypertension was present in 16% of children but was not associated with statistically significant differences in survival outcomes or intra-arrest physiologic measures.
This was a prospectively designed secondary analysis of patients enrolled in the ICU-RESUS clinical trial (NCT02837497).
The primary exposure was a pre-arrest diagnosis of PH.
The primary survival outcome was survival to hospital discharge with favorable neurologic outcome (Pediatric Cerebral Performance Category score 1-3 or unchanged from baseline).
The primary physiologic outcome was event-level average diastolic blood pressure (DBP) during CPR.