ISARIC WHO CCP-UK is a large prospective cohort study of patients in hospital with covid-19. The study continues to enrol at the time of this report. In study participants, mortality was high, independent risk factors were increasing age, male sex, and chronic comorbidity, including obesity.

This study has shown the importance of pandemic preparedness and the need to maintain readiness to launch research studies in response to outbreaks.

The median age of patients admitted to hospital with COVID-19, or with a diagnosis of COVID-19 made in hospital, was 73 years.

More men were admitted than women (men 60%, n=12 068; women 40%, n=8065).

The median duration of symptoms before admission was 4 days (interquartile range 1-8).

The commonest comorbidities were chronic cardiac disease (31%, 5469/17 702), uncomplicated diabetes (21%, 3650/17 599), non-asthmatic chronic pulmonary disease (18%, 3128/17 634), and chronic kidney disease (16%, 2830/17 506); 23% (4161/18 525) had no reported major comorbidity.

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