Join Our 20,000+ Subscribers. Get Weekly News Sent To Your Email
Subscribe to our newsletter and stay updated on the latest Critical Care Medicine related news.
See Past Critical Care Newsletter issues

Subscribe to Newsletter

Polymyxin B‑immobilised Hemoperfusion and Mortality in Critically Ill Patients with Sepsis/Septic Shock

esicm.org February 6, 2018

polymyxin-b‑immobilised-hemoperfusion-and-mortality-in-critically-ill-patients-with-sepsis-septic-shock

Sepsis and septic shock originate from a dysregulated immune response to pathogens and cause millions of deaths worldwide. Endotoxin, a principal component of the outer membrane of Gram-negative bacteria, is a potent trigger of the immune response and high endotoxin levels correlate with worse clinical outcomes. Circulating endotoxin can be removed by Polymyxin B-immobilised hemoperfusion (PMX-HP). PMX-HP has been widely used in clinical practice, however its benefit is uncertain.

meta-analysis mortality sepsis septic shock trial

Strong Ion Difference to Predict Mortality in Septic Shock: Mortality Prediction Model for Admission and 24-hour Mortality

Strong Ion Difference to Predict Mortality in Septic Shock: Mortality Prediction Model for Admission and 24-hour Mortality

72‐h Infusion of Prostacyclin in Mechanically Ventilated Patients with Pulmonary Infection and Endotheliopathy

Shock Indices as Prognostic Indicators: among Sepsis and Septic Shock Patients with and without Comorbidities Presenting to Emergency Department

Shock Indices as Prognostic Indicators: among Sepsis and Septic Shock Patients with and without Comorbidities Presenting to Emergency Department

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill

Little Black Book of Pulmonary Medicine

When Death Becomes Life: Notes from a Transplant Surgeon

Monitoring Mechanical Ventilation Using Ventilator Waveforms

Current Practice Updates in Emergency Medicine

Fleisher & Ludwig’s Textbook of Pediatric Emergency Medicine

Non-Invasive Ventilation and Weaning: Principles and Practice, Second Edition

Hemodynamic Monitoring Using Echocardiography in the Critically Ill

Bedside Procedures in the ICU

Severe Trauma and Sepsis: Organ Damage and Tissue Repair

Evidence-Based Critical Care: A Case Study Approach

Trauma Team Dynamics: A Trauma Crisis Resource Management Manual

ECMO in the Adult Patient (Core Critical Care)

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management