Predicting Sepsis Outcomes – Efficacy of Early Warning Scores

dmlsjournal.com January 28, 2025

In resource-limited settings, NEWS proved to be the most effective tool for early risk stratification in sepsis patients. Its adoption could significantly enhance sepsis management and improve outcomes in emergency departments with constrained resources.

This retrospective study was conducted at the Emergency Department of Khyber Teaching Hospital, Peshawar Pakistan, from January to December 2024.

Patients diagnosed with sepsis based on Sepsis-3 criteria were included. The predictive performance of each EWS was assessed using AUROC, logistic regression, and calibration plots.

NEWS demonstrated superior predictive accuracy for in-hospital mortality (AUROC: 0.873) and ICU admission (AUROC: 0.890) compared to MEWS, qSOFA, and SIRS.