Predictive Utility of DNI in Patients with MOF After Severe Traumatic Injury

sjtrem.biomedcentral.com
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Post-injury multiple organ failure (MOF) is the result of a systemic uncontrolled inflammatory response and it is the one of leading cause of late post-injury mortality. Delta neutrophil index (DNI) may serve useful marker for early diagnosis of inflammatory condition. We ascertained whether DNI might be useful in prediction of post-injury MOF.

Retrospective study of a level 1 trauma center database has been performed from January 2010 to March 2014.

96 patients were enrolled in this study. No differences were found referring to age, gender, laboratory value, injury distribution or overall injury severity between patients with and without MOF.

DNI values were significantly higher in the MOF patients than in the non-MOF patients following 14 days after severe traumatic injury.

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