Patients undergoing mechanical ventilation due to respiratory failure require a comprehensive approach to determine the optimal timing for weaning from ventilatory support.

Evaluating respiratory mechanics, maximal muscle strength, and assessing lung parenchyma and diaphragm function are crucial strategies in this process. Our study underscores the importance of ultrasound, particularly in analyzing both the right and left hemidiaphragms.

Although ultrasound indices alone did not show a definitive association with weaning failure, they provide valuable insights into diaphragmatic function and can enhance the overall assessment strategy.

By integrating ultrasound into a multi-faceted evaluation, clinicians can better navigate the complexities of weaning from mechanical ventilation and potentially improve patient outcomes.

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