Preoperative vitamin D was not associated with a composite of postoperative 30-day cardiac outcomes. However, there was a significant association between vitamin D deficiency and a composite of infectious complications and decreased kidney function.

While renal effects were not clinically meaningful, the effect of vitamin D supplementation on infectious complications requires further study.

A total of 3,851 participants were eligible for analysis.

Preoperative 25-hydroxyvitamin D concentration was 70 ± 30 nmol/l, and 62% of patients were vitamin D deficient.

Overall, 26 patients died, 41 had congestive heart failure or nonfatal cardiac arrest, 540 had myocardial injury, and 15 had strokes.

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