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Prognostic Effect and Longitudinal Hemodynamic Assessment of Borderline Pulmonary Hypertension

jamanetwork.com December 21, 2017

prognostic-effect-and-longitudinal-hemodynamic-assessment-of-borderline-pulmonary-hypertension

Borderline PH is common in patients undergoing RHC and is associated with significant comorbidities, progression to overt PH, and decreased survival. Small increases in mPAP, even at values currently considered normal, are independently associated with increased mortality. Prospective studies are warranted to determine whether early intervention or closer monitoring improves clinical outcomes in these patients. We identified 4343 patients (mean [SD] age, 59 [15] years, 51% women, and 86% white) among whom the prevalence of PH and borderline PH was 62% and 18%, respectively.

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