Prophylactic Haloperidol Effects on Long-term Quality of Life in Critically Ill Patients at High Risk for Delirium
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Prophylactic haloperidol use does not affect long-term quality of life in critically ill patients at high risk for delirium.
Several factors, including the modifiable factor number of sedation-induced coma days, are associated with decline in long-term outcomes.
Of 1,789 study patients, 1,245 intensive care unit patients were approached, of which 887 responded.
Long-term quality of life did not differ between the haloperidol and placebo group.
A preplanned secondary analysis of long-term outcomes of the pRophylactic haloperidol usE for DeliriUm in iCu patients at high risk for dElirium (REDUCE) study was conducted.