This systematic review was able to identify that survivor of critical illnesses experienced changes in worsening quality of life, with impairment also in their functionality in terms of basic and instrumental activities of daily living, within three months after hospital discharge and could become dependents for more than 12 months.

These changes may be associated with risk factors at the time of hospital admission, such as: muscle weakness, depression, sepsis, duration of MV.

The risk factors associated with the potential worsening of quality of life and its subdomains were: depression (one month after discharge from the ICU), frailty, prolonged time on mechanical ventilation and muscle weakness acquired in the ICU.

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