Serum amylase and lipase could serve as independent biomarkers to predict pancreatic injury in critically ill children.

A group of 79 children who died of different causes were investigated by autopsy.

They were divided into pancreatic injury group and pancreatic noninjury group according to autopsy findings. Data based on patients’ demographics, vital signs, laboratory findings, and clinical features at admission were collected and compared.

Logistic regression was used to identify predictive factors for pancreatic injury.

Receiver operating characteristic curve was constructed for assessing serum amylase and serum lipase to predicting pancreatic injury.

41 patients (51.9%) exhibited the pathologic changes of pancreatic injury.

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