The mortality rate was quite high in our study, consistent with the elevated serum biomarker concentrations, which were higher in non-survivors compared with survivors. C-reactive protein (CRP) and IL-6 were the most effective in the sepsis diagnosis.

PCT alone had no good effectiveness, but in combination with CRP and IL-6 has increased the area of certainty in the sepsis diagnosis.

CRP was the most effective in the sepsis prognosis, while Procalcitonin (PCT) and IL-6 had no good effectiveness. However, the combination of these biomarkers could bring an important benefit in the sepsis prognosis.

Further studies are needed to demonstrate the effectiveness of the combination of these biomarkers in the sepsis prognosis.

This study was performed to observe the contribution of inflammatory biomarkers in the diagnosis and prognosis of patients with surgical sepsis.

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