Thyroid storm requiring ICU admission causes high in-ICU mortality. Multiple organ failure and early cardiogenic shock seem to markedly impact the prognosis, suggesting a prompt identification and an aggressive management.

92 patients were included in the study.

Amiodarone-associated thyrotoxicosis and Graves’ disease represented the main thyroid storm etiologies, while hyperthyroidism was unknown in 29 patients (32%) before ICU admission.

Amiodarone use and antithyroid-drug discontinuation were the main thyroid storm-triggering factors.

No triggering factor was identified for 30 patients (33%).

35 patients (38%) developed cardiogenic shock within the first 48 hours after ICU admission.

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