The evaluation of well-appearing term infants for early-onset sepsis (EOS) varies considerably among hospitals, with some doing extensive work-ups and giving antibiotics while others simply observe and provide newborn routine care, a new study has found. Researchers surveyed 97 nurseries participating in the Better Outcomes through Research for Newborns (BORN) network to find out if they used the CDC 2010 perinatal group B streptococcal (GBS) guidelines, AAP guidelines, a sepsis risk calculator or a local approach to assess sepsis risk in well-appearing infants born at 37 weeks' gestation or later.

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