Targeting a mean arterial blood pressure of 77 mm Hg or 63 mm Hg in patients who had been resuscitated from cardiac arrest did not result in significantly different percentages of patients dying or having severe disability or coma.

A total of 789 patients were included in the analysis (393 in the high-target group and 396 in the low-target group).

A primary-outcome event occurred in 133 patients (34%) in the high-target group and in 127 patients (32%) in the low-target group.

At 90 days, 122 patients (31%) in the high-target group and 114 patients (29%) in the low-target group had died (hazard ratio, 1.13; 95% CI, 0.88 to 1.46).

The median CPC was 1 in both the high-target group and the low-target group; the corresponding median modified Rankin scale scores were 1 and 1 , and the corresponding median Montreal Cognitive Assessment scores were 27 and 26.

The median neuron-specific enolase level at 48 hours was also similar in the two groups.

The percentages of patients with adverse events did not differ significantly between the groups.

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