Often misdiagnosed and misunderstood, traumatic brain injury (TBI) may be a life-altering event which can produce a wide range of symptoms affecting physical as well as psychological health. Indeed, all senses can be affected,... read more

There are few jobs that place you on the frontiers of human existence: midwives see lives into the world, undertakers oversee their departure. In between these beginnings and endings, surgeons, doctors and nurses interact... read more

The concepts for good sedation include defining the range of sedation, the need for agents with rapid response that can be easily and rapidly varied in restless and confused patients, various modes of ventilation, continuous... read more

The aim of this study was to evaluate the difference in the time to postintubation sedation between patients receiving etomidate and either succinylcholine or rocuronium in the prehospital setting. This study suggests rocuronium’s... read more

In Shock is a riveting first-hand account from a young critical care physician, who in the passage of a moment is transfigured into a dying patient. This transposition, coincidentally timed at the end of her medical training,... read more

Leveraging real-time data streams from its EHR platform, Penn Medicine has created a dashboard and alerting system to speed the process of getting ICU patients breathing on their own. Many patients in hospital intensive care... read more

Critical Care Pharmacotherapeutics presents information on the fundamentals of critical care practice from a pharmacist’s point of view. This accessible text is an excellent introduction to critical care pharmacy. Pharmacy... read more

For the past 467 days, Zei Uwadia has been hospitalized on life support — but that hasn’t kept the quiet-natured teenager from walking, eating her favorite foods or even doing planks as exercise. Now, with determination... read more

Antibiotics for Sepsis – Does Each Hour Really Count? Or is it Incestuous Amplification? – by Prof Mervyn Singer “Each hour’s delay in initiating antibiotics costs lives” is a doctrine that has... read more

This book provides essential insights into how the approach to nursing care in ICU patients has markedly changed over recent years. It shows how the focus has progressively moved away from the technical approach that characterized... read more

Ultrasound-guided pleural effusion drainage by catheter insertion is a safe and effective procedure. The success rate is low when the effusion is loculated and septated. Both the trocar and the modified Seldinger techniques... read more

Invasive fungal infections (IFIs) are a major cause of morbidity and mortality in critically ill patients. Almost 80% of IFIs are due to Candida spp., which are the third most common isolated microorganisms in the intensive... read more

The liberal use of supplemental oxygen therapy in acutely ill adults has a long history in the hospital, but high-quality therapy supporting its practice is unclear. Recently, the role of oxygen therapy in non-hypoxic patients... read more

We have been searching for a tool to identify myocardial infarction patients who are truly safe for discharge ever since Pope, et al., found that we were discharging two percent of patients with MIs from the emergency department.... read more

Treatment decisions commonly have to be made in intensive care units (ICUs). These decisions are difficult for surrogate decision makers and often lead to decisional conflict, psychological distress, and treatments misaligned... read more

Resting trans-membrane potential difference (Em) of skeletal muscle is correlated to the energy status of the organism: the more severe the illness, the lower the Em. In 1971, Cunningham demonstrated this association with... read more

Patients with isolated traumatic brain injury (TBI) are likely to benefit from effective prehospital care to prevent secondary brain injury. Only a few studies have focused on the impact of advanced interventions in TBI patients... read more

Providing medical dispatchers with visual information from the location of OHCA might improve their understanding of the OHCA-scenario, which might enhance communication, their ability to guide more bystanders and improve... read more

Extracorporeal membrane oxygenation (ECMO), which can support gas exchange or hemodynamics in patients with severe respiratory or cardiac failure, has demonstrated considerable evolution over the last decade [1], with a steady... read more

PS impairment was associated with worse outcomes independently of other markers of chronic health status, particularly for patients in the medium range of severity of illness. PS impairment was moderate in 17.3 % and severe... read more