Anticoagulation in the ICU: Contact Pathway Inhibition Future

Bleeding and thrombotic complications are the main cause of morbidity and mortality in critically ill patients on the intensive care unit (ICU), receiving short-term percutaneous mechanical circulatory support (pMCS) by extracorporeal... read more

Tags: anticoagulation, bleeding, coagulopathy, ECMO, hemostasis, heparin, inflammation, sepsis, thrombosis,

Urine Output-based Sepsis-associated AKI: Clinical Implications

This paper offers comprehensive insights into the epidemiology of acute kidney injury (AKI), and we commend the authors for their significant contribution. They revealed an increase in the number of mild cases among AKI stage... read more

Tags: AKI, creatinine, sepsis, treatment,

Microbial Endocrinology: Interkingdom Signaling in Infectious Disease and Health

This new edition highlights the numerous advances made in the field of microbial endocrinology over the last five years. Prominent among these new topics featured is the emergence of the microbiota-gut-brain axis and the... read more

Tags: book, education, infection, norepinephrine,

A Beginner’s Guide to Vasopressors: Inodilators, Inopressors, Methylene Blue, Midodrine: An Essential Manual to Understanding Cardiac Medications and Cardiovascular Hemodynamic Mechanics

The use of pressors and dilators are common in intensive care units, especially concerning the heart. With different mechanisms of action and titrations, it is essential to know how each of the drugs perform and the potential... read more

Tags: book, education, hemodynamics, ICU, therapy, vasopressors,

Epidemiology of Surgery Associated Acute Kidney Injury (EPIS-AKI)

In a comprehensive multinational study, approximately one in five patients develop PO-AKI after major surgery. Increasing severity of PO-AKI is associated with a progressive increase in adverse outcomes. Our findings indicate... read more

Tags: AKI, diabetes, hypertension, ICU, study, surgery, vasopressors,

Using Deep Neural Networks for Survival Prediction in VA-ECMO

Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is a complex and high-risk life support modality used in severe cardiorespiratory failure. ECMO survival scores are used clinically for patient prognostication and... read more

Tags: arrhythmia, cardiomyopathy, ECMO, myocardial infarction, myocarditis, oxygenation, prognosis, study,

Acute Undifferentiated Fever with Thrombocytopenia: Clinical and Etiological Profile

Prompt recognition and management of thrombocytopenia in acute undifferentiated fever are vital. Thrombocytopenia, along with organ dysfunction and shock, significantly influence patient outcomes. Tailored interventions based... read more

Tags: infection, research, shock, study, thrombocytopenia, transfusion,

Roadblock: AFib with RVR

In this paper we focus on strategies to bypass the most common pitfalls in our treatment algorithm when treating patients who present to the ED in atrial fibrillation with RVR. We all know the few medications in our toolbox... read more

Tags: antibiotics, atrial fibrillation, lactate, sepsis, stenosis, treatment,

Back To The Future: ARDS Guidelines

In June 2023, Intensive Care Medicine published the European Society of Intensive Care Medicine (ESICM) practical guidelines for respiratory support in patients with acute respiratory distress syndrome (ARDS). This monumental... read more

Tags: ARDS, guidelines, PEEP, recommendation,

Introduction to Hemodynamics

This book presents a bibliographical work on the modeling of blood dynamics. The first chapter describes the anatomy of the cardiovascular system and the functioning of the blood circulation. The second chapter is devoted... read more

Tags: blood, book, education, hemodynamics,

What to Know About Merkel Cell Carcinoma, the Rare Cancer that Killed Jimmy Buffett

“Margaritaville” singer Jimmy Buffett died of Merkel cell carcinoma, a rare but aggressive form of skin cancer, according to a tribute posted on his official websiteopens in a new tab or window. The 76-year-old... read more

Tags: cancer, chemotherapy, diagnosis, treatment,

Neonatology Questions and Controversies: Neonatal Hemodynamics

Dr. Richard Polin’s Neonatology Questions and Controversies series highlights the toughest challenges facing physicians and care providers in clinical practice, offering trustworthy guidance on up-to-date diagnostic... read more

Tags: book, diagnosis, education, hemodynamics, neonates, pediatrics, transfusion,

The Hemodynamics of Adrenal Veins with Four-dimensional CT Using Quantitative Time-density Curve

Present study quantitatively analyzed adrenal venous flow using four-dimensional computed tomography (4D CT). We reviewed 4D CT images of 55 patients [mean age, 52 years ± 11 (standard deviation); 23 females] who underwent... read more

Tags: hemodynamics, hypertension, study, tomography,

Floating Feathers: A Doctor’s Harrowing Experience as a Patient Within Conventional Medicine and an Impassioned Call for the Future of Care in America

Dr. Ross I.S. Zbar spent his career as a plastic surgeon, in the US as well as abroad in developing countries, mending disease- and trauma-related deformities–and he was never hesitant to make his voice heard as an...

Monitoring Mechanical Ventilation Using Ventilator Waveforms

This book discusses the interpretation of mechanical ventilator waveforms. Each page shows a screenshot from a real patient and explains one or two messages. It starts with basic information about the waveforms and goes on...